CAS:104481-24-5 2-(1-Piperazinyl)-4-thiazolecarboxylic acid ethyl ester
NAME:2-(1-Piperazinyl)-4-thiazolecarboxylic acid ethyl ester CAS:104481-24-5 MF:C10H15N3O2S MW:241.31 PURITY:98%
Categories:
Material Chemistry
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Product introduction
| NAME | 2-(1-Piperazinyl)-4-thiazolecarboxylic acid ethyl ester |
| CAS | 104481-24-5 |
| MF | C10H15N3O2S |
| MW | 241.31 |
| STORAGE | under inert gas (nitrogen or Argon) at 2–8 °C |
Description
Synthesis Analysis
Ethyl 2-piperazin-1-yl-thiazole-4-carboxylate and its derivatives are synthesized through various methods involving cyclo condensation and nucleophilic substitution reactions. A notable synthesis involves the four-component cyclo condensation of diacetyl, aromatic aldehyde, 2-(piperazin-1-yl)ethanamine, and ammonium acetate using SO4^2−/Y2O3 as a catalyst in ethanol, leading to novel piperazine derivatives with significant antimicrobial activities.
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