CAS:1136-45-4 5-Methyl-3-phenylisoxazole-4-carboxylic acid
NAME:5-Methyl-3-phenylisoxazole-4-carboxylic acid CAS:1136-45-4 MF:C11H9NO3 MW:203.19 PURITY:98%
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Material Chemistry
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Product introduction
| NAME | 5-Methyl-3-phenylisoxazole-4-carboxylic acid |
| CAS | 1136-45-4 |
| MF | C11H9NO3 |
| MW | 203.19 |
| DENSITY | 1.2621 |
| EINECS | 214-497-9 |
| MP | 192-194 °C |
| BP | 341.49°C |
| STORAGE | Keep in dark place,Sealed in dry,Room Temperature |
Description
Synthesis Analysis
The synthesis of isoxazole-4-carboxylic acid derivatives, including 5-methyl-3-phenylisoxazole-4-carboxylic acid, has been achieved through innovative methods. A notable approach involves the domino isoxazole-isoxazole isomerization, catalyzed by Fe(II), leading to isoxazole-4-carboxylic esters and amides with good yields. This process showcases a controlled transformation of 4-acyl-5-methoxy-/5-aminoisoxazoles into desired products under specific conditions .
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