CAS:118994-86-8 5-OXAZOLECARBOXALDEHYDE
NAME:5-OXAZOLECARBOXALDEHYDE CAS:118994-86-8 MF:C4H3NO2 MW:97.07 PURITY:98%
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Material Chemistry
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Product introduction
| NAME | 5-OXAZOLECARBOXALDEHYDE |
| CAS | 118994-86-8 |
| MF | C4H3NO2 |
| MW | 97.07 |
| DENSITY | 1.258±0.06 g/cm3 |
| MP | 30-32℃ |
| BP | 184.7±13.0 °C |
| STORAGE |
Synthesis Analysis
The synthesis of 5-Oxazolecarboxaldehyde has been explored through various methodologies. One notable approach involves the intramolecular Pd(II)-catalyzed cyclization of propargylamides, offering a straightforward pathway to synthesize 2-substituted 5-oxazolecarbaldehydes. This method is well-tolerated by a broad range of aryl, heteroaryl, and alkyl propargylamides, presenting an alternative to the formylation on oxazole rings which often yields unsatisfactory regioselectivity and yields
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