CAS:137553-48-1 4-AMINO-5-FLUOROQUINAZOLINE
NAME:4-AMINO-5-FLUOROQUINAZOLINE CAS:137553-48-1 MF:C8H6FN3 MW:163.15 PURITY:98%
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Life Science Chemicals
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Product introduction
| NAME | 4-AMINO-5-FLUOROQUINAZOLINE |
| CAS | 137553-48-1 |
| MF | C8H6FN3 |
| MW | 163.15163.15 |
| DENSITY | 1.400±0.06 g/cm3 |
| MP | 212-214°C |
| BP | 331.8±27.0 °C |
| STORAGE |
Description
Synthesis Analysis
The synthesis of 5-Fluoroquinazolin-4-amine derivatives often involves multi-step chemical processes. One approach for the synthesis involves starting from 2-amino-4-fluoro benzoic acid and urea, undergoing cyclization, chlorination, and nucleophilic substitution to achieve the target compound with an overall yield of 51%.Another synthesis pathway includes the use of chloroisothiocyanatoquinoline as a derivatizing agent, indicating the versatility in the synthesis approaches for related compounds.
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