CAS:16506-27-7 Bendamustine
NAME:Bendamustine CAS:16506-27-7 MF:C16H21Cl2N3O2 MW:358.26 PURITY:98%
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Product introduction
| NAME | Bendamustine |
| CAS | 16506-27-7 |
| MF | C16H21Cl2N3O2 |
| MW | 358.26 |
| DENSITY | 1.31±0.1 g/cm3 |
| BP | 585.2±50.0 °C |
| STORAGE | 1.31±0.1 g/cm3 |
Description
Bendamustine: Description and Analysis
Bendamustine is a water-soluble, bifunctional chemotherapeutic agent with potential antimetabolite properties, designed in 1963 and re-discovered in the 1990s. It has been used in the treatment of lymphoproliferative disorders and has been designated as an orphan drug in the United States, which confers prolonged market exclusivity . It comprises structural features of both an alkylating drug and a purine nucleoside analog, approved by the US FDA for the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin's lymphoma (NHL) . Bendamustine has shown clinical activity in patients with disease refractory to conventional alkylator chemotherapy and has distinctive preclinical activity in cell lines resistant to other alkylators .
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