CAS:18423-43-3 Deoxythymidine triphosphate
NAME:Deoxythymidine triphosphate CAS:18423-43-3 MF:C10H18N2NaO14P3 MW:506.17 PURITY:98%
Categories:
Material Chemistry
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Product introduction
| NAME | Deoxythymidine triphosphate |
| CAS | 18423-43-3 |
| MF | C10H18N2NaO14P3 |
| MW | 506.17 |
| EINECS | 1806241-263-5 |
| MP | >0°C |
| STORAGE | -20°C |
Description
Synthesis Analysis
Thymidine 5'-triphosphate (TTP) synthesis involves several methods, including a notable one developed in the early 1960s by Ikehara and Ohtsuka. This method achieved TTP synthesis through phosphorylation with specific pyrophosphorochloridates and reaction with pyrophosphate salt, followed by alkaline removal of protecting groups (Ikehara & Ohtsuka, 1963). Additionally, Kore et al. described a "one-pot, three-step" synthetic strategy for the chemical synthesis of sodium salt of 2′-deoxynucleoside-5′-O-triphosphates (dNTPs), including TTP, with yields between 65% to 70%
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