CAS:188198-38-1 2H-1-Benzopyran-4-amine,3,4-dihydro-,(4S)-(9CI)
NAME:2H-1-Benzopyran-4-amine,3,4-dihydro-,(4S)-(9CI) CAS:188198-38-1 MF:C9H11NO MW:149.19 PURITY:98%
Categories:
Material Chemistry
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Product introduction
| NAME | 2H-1-Benzopyran-4-amine,3,4-dihydro-,(4S)-(9CI) |
| CAS | 188198-38-1 |
| MF | C9H11NO |
| MW | 149.19 |
| DENSITY | 1.106±0.06 g/cm3 |
| BP | 237.4±39.0 °C |
| STORAGE | 2-8°C |
Description
Synthesis Analysis
The synthesis of "(S)-Chroman-4-amine" and its derivatives involves various strategies, including asymmetric syntheses which start from substituted chroman-4-ones. A highly enantioselective CBS reduction has been employed to give (S)-chroman-4-ols, which upon azide inversion and reduction yield crude (R)-chroman-4-amines. These can be purified as their (R)-mandelic or d-tartaric acid salts with good yields and excellent enantiomeric excesses
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