CAS:25369-33-9 7-chloroindolin-2-one
NAME:7-chloroindolin-2-one CAS:25369-33-9 MF:C8H6ClNO MW:167.59 PURITY:98%
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Material Chemistry
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Product introduction
| NAME | 7-chloroindolin-2-one |
| CAS | 25369-33-9 |
| MF | C8H6ClNO |
| MW | 167.59 |
| DENSITY | 1.362±0.06 g/cm3 |
| EINECS | 625-279-1 |
| MP | 221-225 °C |
| BP | 341.0±42.0 °C |
| STORAGE | Sealed in dry,Room Temperature |
Description
Synthesis Analysis
The synthesis of indolin-2-one derivatives, including 7-Chloroindolin-2-one, often involves cascade cyclization processes. For example, a method described by Liu et al. (2017) involves a copper-catalyzed cascade annulation of 2-formylbenzonitriles, arenes, and diaryliodonium salts, leading to the formation of 2,3-diarylisoindolin-1-ones, which are closely related to 7-Chloroindolin-2-one. This process highlights the tandem C-N/C-C bond formation, producing isoindolin-1-one derivatives in good to excellent yields.
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