CAS:292135-78-5 RofluMilast N-Oxide
NAME:RofluMilast N-Oxide CAS:292135-78-5 MF:C17H14Cl2F2N2O4 MW:419.21 PURITY:98%
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Material Chemistry
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Product introduction
| NAME | RofluMilast N-Oxide |
| CAS | 292135-78-5 |
| MF | C17H14Cl2F2N2O4 |
| MW | 419.21 |
| DENSITY | 1.56±0.1 g/cm3 |
| EINECS | 604-604-1 |
| MP | 181 °C |
| BP | 519.7±50.0 °C |
| STORAGE | Sealed in dry,Store in freezer, under -20°C |
Description
Roflumilast N-oxide is an active metabolite of roflumilast, a selective phosphodiesterase-4 (PDE4) inhibitor . It is used for the treatment of chronic obstructive pulmonary disease (COPD) and plaque psoriasis . It selectively inhibits the enzyme phosphodiesterase-4 (PDE4), which regulates intracellular cyclic adenosine monophosphate (cAMP) hydrolysis and is involved in immune responses to extracellular stimuli .
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