CAS:3155-48-4 Kavain
NAME:Kavain CAS:3155-48-4 MF:C14H14O3 MW:230.26 PURITY:98%
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Material Chemistry
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Product introduction
| NAME | Kavain |
| CAS | 3155-48-4 |
| MF | C14H14O3 |
| MW | 230.26 |
| DENSITY | 1.15±0.1 g/cm3 |
| MP | 142-148 °C |
| BP | 432.6±45.0 °C |
| STORAGE | Amber Vial, -20°C Freezer, Under inert atmosphere |
Description
Natural kavalactone. Various pharmacological activities including antinociceptive, analgesic, sedative and anticonvulsive activity. Active in vivo and orally bioavailable.
DL-Kawain analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.
Kawain voltage-gated Na+ and L-type Ca2+ channel blocker found in Puper methysticum (kava plant). It displays a variety of biological activities, including protecting against amyloid-β-induced neurotoxicity, suppressing growth of Fusarium, Trichoderma, and Colletotrichum, increasing non-REM sleep time and delta activity during REM sleep, and inhibiting arachidronic acid-induced platelet aggregation and COX expression.
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