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CAS:491-07-6 ISOMENTHONE

NAME:ISOMENTHONE CAS:491-07-6 MF:C10H18O MW:154.25 PURITY:98%

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Material Chemistry

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Product introduction

NAME	ISOMENTHONE
CAS	491-07-6
MF	C10H18O
MW	154.25
DENSITY	0.8389
EINECS	207-727-4
MP	-35 °C
BP	217.64°C
STORAGE	Hygroscopic, Refrigerator, under inert atmosphere

Description
Isomenthone Description and Protective Effects in Human Dermal Fibroblasts
Isomenthone is a naturally occurring compound found in the essential oil of Mentha arvensis L. and is widely used in various industries for its fragrance and flavor. A study has shown that isomenthone exhibits protective effects against cell death induced by tumor necrosis factor-alpha (TNF-α) in human dermal fibroblasts. TNF-α can trigger apoptosis through the activation of c-Jun N-terminal kinase (JNK) and p38 MAPK pathways, which are crucial in stress-induced apoptosis. The research demonstrated that isomenthone could inhibit the reduction in cell viability and the increase in apoptosis caused by TNF-α. This protective mechanism involves the blocking of the JNK and p38 MAPK pathways, preventing the downstream apoptotic events. These findings suggest that isomenthone has potential therapeutic applications in protecting fibroblasts from TNF-α-induced damage .

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