CAS:53312-79-1 3-AMINO-4-CHLOROBENZONITRILE
NAME:3-AMINO-4-CHLOROBENZONITRILE CAS:53312-79-1 MF:C7H5ClN2 MW:152.58 PURITY:98%
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Material Chemistry
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Product introduction
| NAME | 3-AMINO-4-CHLOROBENZONITRILE |
| CAS | 53312-79-1 |
| MF | C7H5ClN2 |
| MW | 152.58 |
| DENSITY | 1.33±0.1 g/cm3 |
| MP | 87-91 °C |
| BP | 292.0±20.0 °C |
| STORAGE | Keep in dark place,Inert atmosphere,Room temperature |
| EINECS | 258-471-5 |
Description
Synthesis Analysis
The synthesis of α-aminonitriles, including compounds like 3-amino-4-chlorobenzonitrile, can be efficiently achieved through multiple pathways. One notable method involves the indium-catalyzed three-component coupling reaction of alkynes, amines, and trimethylsilyl cyanide. This process allows for the production of quaternary α-aminonitrile derivatives, demonstrating a novel approach to synthesizing such compounds (Hamachi et al., 2016). Another innovative synthesis route employs variations of the Blaise reaction, facilitating the synthesis of 3-amino enones and 1,3-diketones from aryl/heteroaryl/alkyl nitriles, showcasing the versatility of nitrile-based reactions
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