CAS:675126-26-8 2-Amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile
NAME:2-Amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile CAS:675126-26-8 MF:C15H19N3O5 MW:321.33 PURITY:98%
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Material Chemistry
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Product introduction
| NAME | 2-Amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile |
| CAS | 675126-26-8 |
| MF | C15H19N3O5 |
| MW | 321.33 |
| EINECS | 1806241-263-5 |
| DENSITY | 1.29 |
| MP | 127℃ |
| BP | 522.3±50.0 °C |
| STORAGE | Sealed in dry,Room Temperature |
Description
Synthesis Analysis
The synthesis of a similar compound, gefitinib, has been reported starting from methyl 3-hydroxy-4-methoxybenzoate . The process involves alkylation of the starting material, followed by nitration, reduction, cyclization, chlorination, and two successive amination reactions . This novel synthetic route produced overall yields as high as 37.4% .
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