CAS:73285-50-4 Deoxynojirimycin hydrochloride
NAME:Deoxynojirimycin hydrochloride CAS:73285-50-4 MF:C6H13NO4 MW:163.17 PURITY:98%
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Material Chemistry
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Product introduction
| NAME | Deoxynojirimycin hydrochloride |
| CAS | 73285-50-4 |
| MF | C6H13NO4 |
| MW | 163.17 |
| MP | 195-196°C |
| STORAGE | Inert atmosphere,2-8°C |
Description
Duvoglustat hydrochloride, also known by its investigational name AT2220, is a pharmacological chaperone under investigation for the treatment of acid α-glucosidase (GAA) deficiency, leading to Pompe disease. This condition is characterized by the progressive accumulation of lysosomal glycogen, primarily affecting heart and skeletal muscles. Preclinical data suggest that oral co-administration of Duvoglustat hydrochloride with enzyme replacement therapy (ERT) increases exposure to active levels of ERT in plasma and skeletal muscles, leading to greater substrate reduction in muscle tissue
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