CAS:850567-34-9 3-(2-THIAZOLYL)AMINOCARBONYLPHENYLBORONIC ACID
NAME:3-(2-THIAZOLYL)AMINOCARBONYLPHENYLBORONIC ACID CAS:850567-34-9 MF:C10H9BN2O3S MW:248.07 PURITY:98% Worldwide Delivery Made in China
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Product introduction
| NAME | 3-(2-THIAZOLYL)AMINOCARBONYLPHENYLBORONIC ACID |
| CAS | 850567-34-9 |
| MF | C10H9BN2O3S |
| MW | 248.07 |
| MP | 218-222 |
| STORAGE | 2-8°C |
Preparation Methods
Synthetic Routes and Reaction Conditions
The synthesis of (3-(Thiazol-2-ylcarbamoyl)phenyl)boronic acid typically involves the reaction of 3-bromophenylboronic acid with thiazole-2-carboxamide under Suzuki-Miyaura coupling conditions . This reaction is catalyzed by palladium and requires a base, such as potassium carbonate, in an aqueous or alcoholic solvent. The reaction is usually carried out under an inert atmosphere at elevated temperatures.
Industrial Production Methods
Industrial production of this compound follows similar synthetic routes but on a larger scale. The process involves the use of high-efficiency reactors and continuous flow systems to ensure consistent product quality and yield. The reaction conditions are optimized to minimize by-products and maximize the efficiency of the palladium catalyst.
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