CAS:882697-00-9 3-(1,3-benzodioxol-5-yl)-5-(3-bromophenyl)-1H-pyrazole
NAME:3-(1,3-benzodioxol-5-yl)-5-(3-bromophenyl)-1H-pyrazole CAS:882697-00-9 MF:C16H11BrN2O2 MW:343.17 PURITY:98%
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Material Chemistry
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Product introduction
| NAME | 3-(1,3-benzodioxol-5-yl)-5-(3-bromophenyl)-1H-pyrazole |
| CAS | 882697-00-9 |
| MF | C16H11BrN2O2 |
| MW | 343.17 |
| DENSITY | 1.567±0.06 g/cm3 |
| BP | 527.3±50.0 °C |
| STORAGE | 2-8°C |
Description
Anle138b is a clinical drug candidate that has shown efficacy in reducing tau aggregates and rescuing disease phenotypes in neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and prion diseases . It is an oligomeric aggregation inhibitor that inhibits the formation of pathological prion protein (PrPSc) and α-synuclein aggregates in vitro . Anle138b prevents the accumulation of PrPSc in the brain and spleen, and prolongs the survival of prion-infected mice .
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