CAS NO.31930-18-4 2-AMINO-4-NITROBENZAMIDE
NAME:2-AMINO-4-NITROBENZAMIDE CAS:31930-18-4 MF:C7H7N3O3 MW:181.15 PURITY:98%
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Material Chemistry
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Product introduction
| NAME | 2-AMINO-4-NITROBENZAMIDE |
| CAS | 31930-18-4 |
| MF | C7H7N3O3 |
| MW | 181.15 |
| MP | 222-224 °C |
| DENSITY | 1.481±0.06 g/cm3 |
| STORAGE | Keep in dark place,Inert atmosphere,Room temperature |
Description:
The synthesis of 2-Amino-4-nitrobenzamide and its derivatives has been reported in several studies . For instance, a series of 2-chloro-5-[(4-chlorophenyl)sulfamoyl]-N-(alkyl/aryl)-4-nitrobenzamide derivatives has been synthesized and confirmed by physicochemical and spectral means . Another study reported the synthesis of benzamides through direct condensation of carboxylic acids and amines in the presence of diatomite earth@IL/ZrCl4 under ultrasonic irradiation .
Applications:
Bioactivation and Cytotoxicity : 2-Amino-4-nitrobenzamide derivatives have been studied for their role in bioactivation and cytotoxicity. For example, 4-hydroxylamino derivatives of 2-nitrobenzamide, like CB 1954, are known for their selective cytotoxicity due to their ability to form DNA-DNA interstrand crosslinks in cells .
Chemotherapeutic Potential : Some derivatives of 2-Amino-4-nitrobenzamide show potential chemotherapeutic activity. For instance, 4-iodo-3-nitrobenzamide and its reduction to 4-iodo-3-aminobenzamide have been tested for their action against various tumor cells, showing promising results in inducing cell death in cancer cells .
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