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CAS NO.498-23-7 Citraconic acid

NAME:Citraconic acid CAS:498-23-7 MF:C5H6O4 MW:130.1 PURITY:98%

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Material Chemistry

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NAME	Citraconic acid
CAS	498-23-7
MF	C5H6O4
MW	130.1
EINECS	207-858-7
DENSITY	1,62 g/cm3
MP	88-94 °C
STORAGE	Hygroscopic, -20°C Freezer, Under inert atmosphere
FORM	Hygroscopic, -20°C Freezer, Under inert atmosphere

Description:
Citraconic acid is an organic compound with the formula CH3C2H(CO2H)2. It is a white solid and the alkene is cis . The related trans alkene is called mesaconic acid . It is one of the pyrocitric acids formed upon the heating of citric acid .
Citraconic acid can be produced, albeit inefficiently, by oxidation of xylene and methylbutanols . In the laboratory, citraconic acid can be produced by thermal isomerization of itaconic acid anhydride to give citraconic anhydride, which can be hydrolyzed to citraconic acid . The required itaconic acid anhydride is obtained by dry distillation of citric acid.
Biomedical Applications:
Citraconic acid derivatives, particularly in the form of citrate-based polymers, have shown promise in various biomedical applications. These polymers are valued for their biodegradability, biocompatibility, and antimicrobial properties, making them suitable for wound dressing, tissue engineering, and other medical applications where antimicrobial properties are desired. Poly(octamethylene citrate) exhibited significant suppression of microbial proliferation, highlighting the potential of citrate-based polymers in preventing bacterial growth without the need for traditional antibacterial agents.

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