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CAS NO:1138245-13-2 Mirogabalin

CAS NO:1138245-13-2 NAME:Mirogabalin MF：C12H19NO2 MW：209.28 Purity:98% Appearance:white powder COA:Provide Sample:Negotiable

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Life Science Chemicals

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Product introduction

PRODUCT NAME	Mirogabalin
CAS NO	1138245-13-2
Other name	2-((1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid
BP	357.5±15.0 °C(Predicted)
DENSITY	1.104±0.06 g/cm3(Predicted)
STORAGE	2-8°C
DELIVERY	2-3DAYS
PACKAGE	According client's request

Description of CAS NO:1138245-13-2 Mirogabalin

Mirogabalin, also known as DS-5565 CAS NO:1138245-13-2 , is a gabapentinoid medication developed by Daiichi Sankyo . It is a member of the gabapentinoid class, which also includes gabapentin and pregabalin . As a gabapentinoid, mirogabalin binds to the α2δ subunit of voltage-gated calcium channels (1 and 2), but with significantly higher potency than pregabalin . It has shown promising results in Phase II clinical trials for the treatment of diabetic peripheral neuropathic pain .

Applications of CAS NO:1138245-13-2 Mirogabalin

1.Analgesic Effects in Fibromyalgia Models

2.Approval for Peripheral Neuropathic Pain

3.Treatment of Diabetic Neuropathy and Postherpetic Neuropathy : Mirogabalin is effective and safe in treating neuropathic pain in diabetic neuropathy and postherpetic neuropathy, with potential applications in other neuropathic pain etiologies

4.Use in Renal Impairment and Pain Associated with DPNP or PHN : Mirogabalin was well tolerated and significantly reduced pain levels in Japanese patients with renal impairment suffering from diabetic peripheral neuropathic pain or post-herpetic neuralgia

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