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CAS NO:1138245-21-2 Mirogabalin besylate

CAS NO:1138245-21-2 Mirogabalin besylate

CAS NO:1138245-21-2 NAME:Mirogabalin besylate MF：C18H25NO5S MW：367.46 Purity:98% Appearance:white powder COA:Provide Sample:Negotiable

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Product introduction

PRODUCT NAME	Mirogabalin besylate
CAS NO	1138245-21-2
Other name	2-((1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid besylate
STORAGE	2-8°C
DELIVERY	2-3DAYS
PACKAGE	According client's request

Description of CAS NO:1138245-21-2 Mirogabalin besylate

Mirogabalin besylate CAS NO:1138245-21-2 is a drug that is used to treat neuropathic pain, postherpetic neuralgia, and other disorders. Mirogabalin besylate is an analog of gabapentin with increased solubility in water and a decreased solubility in organic solvents. Mirogabalin besylate has been shown to be safe and have a good efficacy profile in clinical development. It has also been shown to be effective in the treatment of depression.

Mirogabalin besylate (DS-5565)CAS NO:1138245-21-2 is a novel potent, selective ligand of the α2δ subunit of voltage-gated calcium channels . It is a member of the gabapentinoid drug class, which includes gabapentin and pregabalin . Mirogabalin was developed by Daiichi Sankyo and was first approved in Japan for the treatment of peripheral neuropathic pain (PNP), including diabetic PNP and postherpetic neuralgia .

Applications of CAS NO:1138245-21-2 Mirogabalin besylate

1.Treatment of Peripheral Neuropathic Pain

2.Analgesic Effects in Fibromyalgia Models

3.Treatment of Postherpetic Neuralgia

4.Anxiolytic Effects in Neuropathic Pain Model

Future Directions:

Mirogabalin besylate shows promise as a novel, safe gabapentinoid anticonvulsant with a greater therapeutic effect for neuropathic pain in the dorsal root ganglion and lower adverse drug reactions in the cerebellum . Further studies are needed to explore the role of mirogabalin in cancer pain, postoperative pain, and neuropathic pain due to various other etiologies .

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