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CAS NO:23235-03-2 H-D-Pra-OH

NAME:D-PROPARGYLGLYCINE/H-D-Pra-OH CAS NO:23235-03-2 MF：C5H7NO2 MW：113.11 PURITY:95%MIN APPEARANCE:White to pale yellow Powder COA:Provide Sample:Negotiable

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PRODUCT NAME	H-D-Pra-OH / D-PROPARGYLGLYCINE
CAS NO	23235-03-2
MP	205-207 °C(lit.)
BP	583.5±50.0 °C(Predicted)
DENSITY	1.242±0.06 g/cm3(Predicted)
STORAGE	2-8°C
DELIVERY	2-3DAYS
PACKAGE	According client's request

Description of H-D-Pra-OH CAS NO:23235-03-2

H-D-Pra-OH (D-PROPARGYLGLYCINE ) CAS NO:23235-03-2 is a chemical substance that inhibits the synthesis of proteins. It binds to the active site of enzymes, thereby blocking the formation of an enzyme-substrate complex and inhibiting enzyme activity. H-D-Pra-OH is an enzyme inhibitor that can be used to study protein synthesis in vitro. It is most effective on renal proximal tubules cells, where it inhibits potassium uptake by competitive inhibition with d-alanine. H-D-Pra-OH also inhibits the uptake of aziridine, which is a reactive substance that can cause cellular damage. The carbonyl group in this substance may react with other substances such as potassium dichromate, forming a chromium compound that can be seen under the microscope.

Applications of H-D-Pra-OH CAS NO:23235-03-2

1)Inhibition of Enzymes and Metabolic Pathways
D-Propargylglycine has been identified as an inhibitor of various enzymes and metabolic pathways.

2)Potential Role in Hydrogen Sulphide Modulation
D-Propargylglycine has been studied for its potential role in modulating hydrogen sulphide, particularly in the context of erectile dysfunction.

3)Impact on Amino Acid Metabolism

4)Role in Anticancer Drug Resistance
D-Propargylglycine has been studied for its potential impact on drug resistance in cancer therapy.

5)Effects on Postharvest Changes in Horticultural Produce
There is also research exploring the use of D-Propargylglycine in horticulture, particularly in the storage of horticultural produce like pak choy

6)Exploring Peptide Conformation Dynamics
The influence of D-Propargylglycine on the conformational dynamics of peptides has been a topic of interest. Its incorporation in peptides can significantly alter their backbone conformations, thus contributing to the understanding of peptide structure and function.

Future Directions
D-Propargylglycine has been used in the synthesis of a DNA nanodevice-based vaccine for cancer immunotherapy . The peptide–DNA conjugates were synthesized by attaching azide-modified oligonucleotides to peptides containing a propargylglycine at the C terminus, through click chemistry . This represents a promising direction for the future use of D-Propargylglycine in medical research and treatment .

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