Fluralaner CAS NO:864731-61-3
NAME:Fluralaner CAS NO:864731-61-3 Formula Weight:556.29 Purity:≥98% Appearance:A crystalline solid Molecular Formula:C22 H17 Cl2 F6 N3 O3 Applications: Fluralaner is an insecticide and acaricide used to treat Sarcoptes scabiei var. canis infestation in dogs. Flea treatment. A possible anti-malarial found to kill disease-spreading mosquitoes when they bite treated people. Description: Fluralaner is an isoxazoline ectoparasiticide. It potently and selectively inhibits binding of the GABA receptor channel blocker EBOB to housefly head membranes
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Life Science Chemicals
Pharmaceutical Intermediates
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Product introduction
| PRODUCT NAME | Fluralaner |
| CAS NO | 864731-61-3 |
| MF | C22 H17 Cl2 F6 N3 O3 |
| MW | 556.29 |
| PURITY | ≥98% |
| APPEARANCE | A crystalline solid |
| PACKAGE | According client's request |
| DELIVERY | 2-3days |
| STORAGE | A crystalline solid |
| COA | Provide |
Synonyms:
4-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-2-methyl-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-benzamide;
A 1443, Fluralaner, Bravecto, AH 252723,4-[5-(3,5-Dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-2-methyl-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]benzamide;
Fluralaner CAS NO:864731-61-3 is a novel insecticide that has been developed to target fleas, ticks, and other arthropods. It is a highly effective insecticide that has been used in veterinary and agricultural applications for several years. It is a member of the isoxazoline family of insecticides, which are known for their broad-spectrum activity and low toxicity. Fluralaner is a systemic insecticide, meaning that it is taken up by the plant or animal and distributed throughout its body. This makes it an effective treatment for fleas, ticks, and other arthropods.
Scientific research applications
Enantioselective Detection and Bioactivity
Fluralaner CAS NO:864731-61-3 is a chiral isoxazoline insecticide with significant insecticidal and acaricidal activity.
Differential Mechanisms of Action on GABA Receptors
Fluralaner CAS NO:864731-61-3 acts as an antagonist of γ-aminobutyric acid (GABA) receptors, showing high pest control activities against pests resistant to other pesticides like fipronil.
Pharmacokinetics in Dogs
Fluralaner CAS NO:864731-61-3 has been studied for its pharmacokinetics in dogs.
Transcriptome and Gene Response in Spodoptera litura
Fluralaner's impact on the common cutworm, Spodoptera litura, was assessedthrough transcriptome analysis and gene response studies.
Toxicity and Sublethal Effects on Spodoptera litura
Research on Spodoptera litura, a polyphagous pest, revealed fluralaner's high toxicity via topical or oral application.
Acute Toxicity and Antioxidant Effects in Zebrafish
A study on zebrafish demonstrated fluralaner's low toxicity and rapid elimination after exposure in clean water
Molecular Interactions with Lipid Membranes
Recent research explored fluralaner's interactions with lipid membranes, focusing on its potential to bioaccumulate and reach toxic local concentrations. This study provides crucial information on fluralaner's penetration, holding, and accumulation in membranes, with implications for its environmental and health impact
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