Ibutilide Hemifumarate CAS no:122647-32-9
product name:Ibutilide Hemifumarate CAS:122647-32-9 Description: Blocks IKr, hERG and L-type Ca2+ channels; class III antiarrhythmic
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Life Science Chemicals
Pharmaceutical Intermediates
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Product introduction
| PRODUCT NAME | Ibutilide Hemifumarate |
| CAS NO | 122647-32-9 |
| EINECS NO | 687-381-2 |
| MF | (C20H36N2O3S)2.C4H4O4 |
| DENSITY | 1.3647 (rough estimate) |
| STORAGE | 2-8°C |
| DELIVERY | 2-3DAYS |
| PACKAGE | According client's request |
Description of Ibutilide CAS:122647-32-9
Ibutilide CAS:122647-32-9 is a class III antiarrhythmic drug that acts by inhibiting the rapid influx of calcium ions into cardiac cells. It has been shown to reduce fibrillation in patients with structural heart disease, and also to control ventricular rate in atrial fibrillation. Ibutilide has been found to have synergistic effects when combined with other pharmacological agents, such as amiodarone, procainamide, or lidocaine.
Applications of Ibutilide CAS:122647-32-9
It is primarily used to treat atrial fibrillation and atrial flutter by prolonging the action potential duration and refractory periods in the heart. This compound works by activating a slow, inward sodium current rather than blocking outward potassium currents.
Chemistry: It is used as a reference compound in studies involving antiarrhythmic agents and ion channel blockers.
Biology: Ibutilide is used to study the effects of ion channel modulation on cellular processes.
Medicine: The compound is used in clinical research to develop new treatments for cardiac arrhythmias.
Industry: This compound is used in the pharmaceutical industry for the development of antiarrhythmic drugs.
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